| 1 | Transformers: Revenge of... - $112M |
| 2 | The Proposal - $18.5M |
| 3 | The Hangover - $17.2M |
| 4 | Up - $13M |
| 5 | My Sister's Keeper - $12M |
| 6 | Year One - $5.8M |
| 7 | The Taking of Pelham 123 - $5.4M |
| 8 | Star Trek - $3.6M |
| 9 | Night at the Museum: Battle... - $3.5M |
| 10 | Away We Go - $1.7M |
